Tottenham manager Mauricio Pochettino admitted he may rest players against Borussia Dortmund on Tuesday, but said Danny Rose is in contention to start.
Spurs have already qualified for the Champions League round of 16 and need only one victory from their two remaining games to progress as winners of Group H.
It means Pochettino is likely to take the chance to rotate his lineup, which could include a start for Rose, who was left out of the squad completely for Saturday's north London derby.
Real Madrid coach Zinedine Zidane said that although others outside the club might be "worried" by his team's form, he remains convinced that they will come good again by the end of the season.
Double Champions League holders Madrid have just one point from their last two Group H outings, at home and away against Tottenham, but can still ensure progress to the last 16 with a win in Tuesday's game at APOEL Nicosia.
Stumbles in La Liga this season have had more serious consequences, with Zidane's...
Real Madrid head coach Zinedine Zidane is preparing his players for the Champions League meeting with Apoel Nicosia as if it were a second derby of the week.
Los Blancos shared a rare goalless draw with city rivals Atletico Madrid on Saturday, a result that boosted Barcelona's hopes of winning LaLiga, and just two days later Real left for Cyprus for a match against opposition they beat 3-0 in September.
``We want to show the same determination we demonstrated against Atletico. We are one step away...